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HelpTest Code T821Q RUNX1-RUNX1T1 Translocation (8;21), Minimal Residual Disease Monitoring, Quantitative, Varies
Shipping Instructions
1. Refrigerated specimens must arrive within 5 days of collection, and ambient specimens must arrive within 3 days of collection.
2. Collect and package specimen as close to shipping time as possible.
Necessary Information
The following information is required:
1. Pertinent clinical history
2. Date of collection
3. Specimen source (blood or bone marrow)
Specimen Required
Submit only 1 of the following specimens:
Specimen Type: Blood
Container/Tube: Lavender top (EDTA) or yellow top (ACD-B)
Specimen Volume: 10 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
3. Label specimen as blood.
Specimen Type: Bone marrow aspirate
Container/Tube: Lavender top (EDTA) or yellow top (ACD-B)
Specimen Volume: 4 mL
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send bone marrow specimen in original tube. Do not aliquot.
3. Label specimen as bone marrow.
Forms
1. Hematopathology Patient Information (T676)
2. If not ordering electronically, complete, print, and send an Hematopathology/Cytogenetics Test Request (T726) with the specimen.
Secondary ID
615905Useful For
Detection of RUNX1-RUNX1T1 gene fusion in acute myeloid leukemia patients at the time of diagnosis
Minimal residual disease monitoring during the clinical and therapeutic course of these patients
Method Name
Quantitative Real-Time Reverse Transcription Polymerase Chain Reaction (qRT-PCR)
Reporting Name
RUNX1/RUNX1T1, t(8;21), Quant, VSpecimen Type
VariesSpecimen Minimum Volume
Peripheral blood: 8 mL
Bone marrow: 2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Varies | Refrigerated (preferred) | 5 days | |
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Bone marrow core biopsies Heparin sample Paraffin-embedded bone marrow clots Slides Paraffin shavings Moderately to severely clotted |
Reject |
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Saturday
Report Available
4 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81401
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| T821Q | RUNX1/RUNX1T1, t(8;21), Quant, V | 72207-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MP061 | Specimen Type | 31208-2 |
| 615906 | Interpretation | 69047-9 |
| 616034 | Signing Pathologist | 18771-6 |